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Relieve Chronic Pain at the Source

Advanced Nano Delivery System

Targets pain at the cellular level

19 Natural Ingredients sourced in the USA

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23K+ Customers

60 day guarantee

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bestseller

NanoXtreme Starter Pack

$59.99

"NanoXtreme has been an amazing addition to my practice. I use the solution for my patients with painful muscle spasms, athletes seeking muscle recovery maintenance.

Dr. Natalie

NanoXtreme 3.3oz Airless Pump Bottle

$49.99

NanoXtreme 3.3oz Tube

$49.99

"NanoXtreme has been an amazing addition to my practice. I use the solution for my patients with painful muscle spasms, athletes seeking muscle recovery maintenance.

Dr. Natalie

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Advanced Pain-Relieving Cream Powered by Nanotechnology

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Targeted relief

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NanoXtreme targets pain at its source. The nano-sized molecules penetrate all seven layers of skin, and fight the discomfort at the cellular level.

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Muscle & nerve relief

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Our nanoparticles absorb into the muscle tissues and tendons, while stimulating nerve receptors providing support where it's needed most.

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Fights Inflammation

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Formulated with powerful anti-inflammatories, NanoXtreme helps reduce swelling and discomfort over time.

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Enhanced Bioavailability

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Improves molecule stability, ensuring each drop is packed with relief and faster-acting than other topicals.

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The NanoXtreme Advantage

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A cutting-edge topical pain relief cream designed to target pain at its source. NanoXtreme utilizes advanced nanotechnology, that penetrates deep into the skin to deliver its powerful, natural ingredients using Nanotechnology.

A cutting-edge topical pain relief cream designed to target pain at its source.


NanoXtreme utilizes advanced nanotechnology, that penetrates deep into the skin to deliver its powerful, natural ingredients using Nanotechnology.

A tube of Nano Xtreme Pain Relieving Cream over an anatomical illustration of a human knee joint.

Trusted & Loved by Physicians

“The way NanoXtreme product reduces inflammation is astonishing”

Dr. Natalie Rosenzweig

licensed chiropractic physician

The way NanoXtreme product reduces inflammation is astonishing and has improved patient care and outcomes. It lasts all day post treatment and patients report feeling the warming effect reactivate later in the day. I highly recommend this product to other chiropractors/PTs, and athletes looking for a way to relieve their muscle aches at home.

Dr. Natalie Rosenzweig

licensed chiropractic physician

What our customers are saying

A tube of Nano Xtreme Pain Relieving Cream with icons highlighting superior absorption, fast relief, and being made in the USA.

Frequently Asked Questions

4.8 (821 reviews)

NanoXtreme PAIN-Relief CREAM

NanoXtreme

PAIN-Relief CREAM

Relieve Chronic Pain at the Source.

Each tube is 3.3oz 100ml (approx. 1 month supply). TSA carry-on compliant for no-hassle travel.

4.8 (821 reviews)

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$39.99 EACH

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$49.99

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Frequently Asked Questions

Story Behind NanoXtreme

The pain cream's origins span over 60 years, but NanoXtreme began in March 2023. Chief Chemist Mikel Anderson's son, Mikey, nearly dropped out of a tennis tournament due to a shoulder injury. Mikel refined a pain formula for 18 hours. Remarkably, Mikey regained mobility in five minutes with minimal pain and won the tournament.

Mikel unknowingly created something revolutionary. Later, clients inquired about other products but only mentioned the cream, including Michael Grondahl, Founder of Planet Fitness, who became a partner.

Got Questions? We’ve Got Answers

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Nanoxtreme

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